R&D budget has been recently increased rapidly by the Korean government's direction under the recognition that a strong R&D policy leads to the wealth of the nation. The methodologies for effective evaluation that have received great attention were increased. We had established the laws to evaluate and manage the performance of national R&D programs in 2005. The previous and current R&D evaluation programs were conducted in the middle of progress. Recently, the importance of evaluation of follow-up control conducted after finishing the program at the national level is increasing. The purposes of this study are to evaluate national R&D programs in terms of economic impacts and to develop the efficient methodologies by considering follow-up evaluation. This study will be effective to demonstrate the efficiency of the methodologies based on follow-up evaluation and the necessity of the evaluation of R&D programs after wrapping up the programs.